I mean... Holo will go bankrupt, be bought out and rebranded or fade into obscurity some day, that's just how companies work. I REALLY DOUBT it will be any time soon though, given that their only semi-threatening competition just shot themselves in the foot and took themselves out of the EN market altogether.
Whenever Holo breathes its last vtubing will probably be radically different, maybe vtubing will die somewhere along the way and Holo will live on doing multimedia like bushiroad, who knows? The life of intangible entities like companies cannot be measured like the life of people, which is definitely finite. The only definitive thing is that their influence on vtubing history and internet culture is undeniable and will always be tied to the medium, even if they go away it will be impossible to have people forget what was. I'd honestly prefer the company to implode suddenly one day rather than slowly waste away and become a shell of its former self like many others.