You don't climb out from under severe anxiety and major depression with a good friend, its a negative thought spiral and Pippa has admitted to having them. She legitimately needs cognitive behavioral therapy.
You do, actually. Funny you seem to think the anxiety and depression aren't completely caused by her surroundings. A good friend would hopefully help by getting her out of the house for most days so she stops being stuck to her computer 16h/24 and finds things to enjoy in real life. Then maybe some kind of physical activity would help her anxiety a lot.
Then after that maybe she realizes that working on improving your real life is also important instead of letting everything around decay, even your body while you're mindlessly focused on your job and entertainment.
Then maybe after that she realizes she's not, in fact, asexual, but was just depressed and decides to marry the only man willing to help fix her.
"Marrying will surely improve my self-diagnosed anxiety and depression! This can only end well!"
Unironically, yes. But that was not my point, first she gets fixed, then she marries Reticule as part of her self-improvement journey.
You hear some pretty wild takes on mental health on the internet but this is the first time that I've heard someone claim that anxiety was caused by not tidying your room.
I can tell I'm going down an autism spiral trying to justify my point of view, so here's hoping you understand what I'm trying to say, because I'm going to need to stop being autistic.
Therapists aren't these magicians that can miraculously heal you, and meds don't just cure depression, they numb feelings and in Pippa's case would make things worse as they would make her okay with her situation and make her more depressed.
The computer is this nice entertaining activity we all partake in, but in cases where you spend most of your life on it, it becomes this nice blanket where you get to ignore your bad feelings about your current situation because it keeps you continually entertained and unable to think about what's making you feel so bad.
Have you ever thought about why so many women are so anxious ? Could it be they're feeling anxious because their life is stagnant but society is telling them that being independent and having a job is good, so they end up mentally stuck. And to try to cope they go commit vices or look to doctors who don't understand them.
What I was trying to describe is actually facing those bad feelings and thinking to yourself "Why am I feeling this way ?" "Where do I actually want to be ?" etc ... All the while keeping a healthy lifestyle so you have the energy to ask those questions and continually look for answers without giving up because you're tired or whatever excuse.
(Queue people dismissing this because my optimism is repulsive to their defeatist mindset)