It's been known there was something really broken with her hormones, though this is the first time I can recall mentioning details. Though the lack of emotional responses explains quite a lot of things, frankly. It's the same escalation as the drug cycle causes. Off the top of my head, I'm guessing there's probably a pretty substantial misdiagnosis and they've sent her around the ringer for years. But, sadly, that isn't surprising. Functionally, her body is going from 100 to 0, which is likely causing the Super Horny to Depressive episodes. Sounds a bit like an active hormonal growth. Most of the hormone-producing organs are prone to growths. Vast majority are non-active, but the active ones cause issues like that with spikes & crashes. At least in some cases. If it was sub-critical levels and matched with heavy cell surface sensitivity, it'd fit the mold for the issues as she's described them in the bits I've caught.